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Platelet Counts Further Refine Classification of Renal-Cell Carcinoma

января 28, 2021

French and Italian researchers designed a study to improve treatment options for patients with clear-cell renal-cell carcinoma (ccRCC) at intermediate-risk by better characterizing their classification. RCC Renal Cell Carcinoma Written on Green Key of Metallic Keyboard. Finger pressing key. Listen to an audio version of this article A treatment plan for patients with cancer depends acutely on the current stage and progression rate it is discovered in, as well as the type of cancer it is. The more precisely a patients’ risk can be assessed, the more exact their treatment plan can be. This leads directly to better patient outcomes. One way to gauge a patients’ risk is to use a risk-stratified method. Risk stratification is the systematic classification of patients based on the current status of their health and the number of negative clinical prognostic factors that they present with. From Gustave Roussy, the Gustave Roussy Institute, and the University of Paris-Saclay—each in Villejui

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hospitals in us

января 27, 2021

When public mention contemporary medicine, accuracy plays one of the most important roles and people’s lives are directly dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the highest standards. The problem nowadays is that any conclusions of researches can be shared online and used as a reference without being thoroughly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and attempted to come up with an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores

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Metabolism of Breast Cancer Cells Exploited by Amino Acids

января 26, 2021

Researchers from Germany starved breast cancer cells of amino acids, including methionine, and exploited their dependency on the amino acid transporter SLC6A14. oncotarget submission Cancerous tumors are greedy invaders. In order to sustain their signature high rate of growth, proliferation, and to increase their metabolic capacity, tumor cells demand more nutrients from the body, such as glucose and amino acids. One way that tumor cells elevate this intake of nutrients is by increasing the expression of genes that encode amino acid transporters. This knowledge provided new potential therapeutic targets for the authors of the cover paper for Oncotarget’s Vol 11, Issue #48. Twitter Oncotarget “Targeting tumor metabolism has been explored as a strategy to inhibit tumor growth and proliferation due to the elevated metabolic requirements of cancer cells compared to their normal counterparts [1].” Researchers from Germany organized the study, “Exploiting the metabolic dependencies of

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clinics in us

января 26, 2021

When general population discuss modern medicine, accuracy plays one of the most important roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to meet the highest standards. The challenge nowadays is that any conclusions of researches can be shared online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores higher than 100

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clinics in us

января 21, 2021

When people refer to modern medicine, accuracy plays one of the most crucial roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are necessary to comply with the highest standards. The problem nowadays is that any outcomes of researches can be posted online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scores higher than 100 as w

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Novel MicroRNA Identified as Prostate Cancer Biomarker

января 21, 2021

Researchers based out of the United States identified a new microRNA as a key regulator of stemness and metastasis in prostate cancer cells. Microscopic view of a single mRNA strand. 3D Medical illustration Microscopic view of a single mRNA strand. 3D Medical illustration Listen to an audio version of this article In the United States, the second leading cause of cancer related deaths in men is prostate cancer. While new research and therapies are advancing, a large percentage of patients with this disease continue to progress to the advanced stages. usa hospitals lists For years, researchers have used biological indicators such as the prostate-specific antigen (PSA) to aid in early detection and diagnosis of prostate cancer. This enzyme is derived from prostate tissue, which is released by normal and tumor cells, and plays a role in semen liquefaction. While serum PSA quantities often correlate with prostate volume, the researchers in this study say that the PSA is not the most opt

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