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When general population speak of modern medicine, precision plays one of the most important roles and human lives are literally dependent on it. Hence, any researches related to medicine are necessary to comply with the top standards. The challenge today is that any recommendations of researches can be shared online and used as a reference without being thoroughly checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That helps both readers and authors to verify publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective scores above

French and Italian researchers designed a study to improve treatment options for patients with clear-cell renal-cell carcinoma (ccRCC) at intermediate-risk by better characterizing their classification. RCC Renal Cell Carcinoma Written on Green Key of Metallic Keyboard. Finger pressing key. Listen to an audio version of this article A treatment plan for patients with cancer depends acutely on the current stage and progression rate it is discovered in, as well as the type of cancer it is. The more precisely a patients’ risk can be assessed, the more exact their treatment plan can be. This leads directly to better patient outcomes. One way to gauge a patients’ risk is to use a risk-stratified method. Risk stratification is the systematic classification of patients based on the current status of their health and the number of negative clinical prognostic factors that they present with. From Gustave Roussy, the Gustave Roussy Institute, and the University of Paris-Saclay—each in Villejui

When public mention contemporary medicine, accuracy plays one of the most important roles and people’s lives are directly dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the highest standards. The problem nowadays is that any conclusions of researches can be shared online and used as a reference without being thoroughly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and attempted to come up with an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores

Researchers from Germany starved breast cancer cells of amino acids, including methionine, and exploited their dependency on the amino acid transporter SLC6A14. oncotarget submission Cancerous tumors are greedy invaders. In order to sustain their signature high rate of growth, proliferation, and to increase their metabolic capacity, tumor cells demand more nutrients from the body, such as glucose and amino acids. One way that tumor cells elevate this intake of nutrients is by increasing the expression of genes that encode amino acid transporters. This knowledge provided new potential therapeutic targets for the authors of the cover paper for Oncotarget’s Vol 11, Issue #48. Twitter Oncotarget “Targeting tumor metabolism has been explored as a strategy to inhibit tumor growth and proliferation due to the elevated metabolic requirements of cancer cells compared to their normal counterparts [1].” Researchers from Germany organized the study, “Exploiting the metabolic dependencies of

When general population discuss modern medicine, accuracy plays one of the most important roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to meet the highest standards. The challenge nowadays is that any conclusions of researches can be shared online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores higher than 100

When people refer to modern medicine, accuracy plays one of the most crucial roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are necessary to comply with the highest standards. The problem nowadays is that any outcomes of researches can be posted online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scores higher than 100 as w

Researchers based out of the United States identified a new microRNA as a key regulator of stemness and metastasis in prostate cancer cells. Microscopic view of a single mRNA strand. 3D Medical illustration Microscopic view of a single mRNA strand. 3D Medical illustration Listen to an audio version of this article In the United States, the second leading cause of cancer related deaths in men is prostate cancer. While new research and therapies are advancing, a large percentage of patients with this disease continue to progress to the advanced stages. usa hospitals lists For years, researchers have used biological indicators such as the prostate-specific antigen (PSA) to aid in early detection and diagnosis of prostate cancer. This enzyme is derived from prostate tissue, which is released by normal and tumor cells, and plays a role in semen liquefaction. While serum PSA quantities often correlate with prostate volume, the researchers in this study say that the PSA is not the most opt

When public mention today’s medicine, precision plays one of the most crucial roles and people’s lives are literally dependent on it. Hence, any researches related to medicine are required to comply with the highest standards. The challenge today is that any outcomes of researches can be shared online and used as a reference without being precisely checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality indicator. That allows both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a complete publications list with respective scores higher than 100 as we

“The current study is the first of its kind, wherein comprehensive transcriptome analysis using RNA-Seq was performed in Notch2 depleted B-cell lymphoma cells.” Malignant effusion cytology: microscopic image of diffuse large B-cell lymphoma, a type of non Hodgkin lymphoma. Malignant effusion cytology: microscopic image of diffuse large B-cell lymphoma, a type of non Hodgkin lymphoma. The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here, and at Oncotarget.com. oncotarget journal Splenic marginal zone lymphoma (SMZL) is a rare subtype of non-Hodgkin lymphoma that comprises approximately 10% of all lymphoma cases. Marginal zone lymphoma (MZL) originates from B memory lymphocytes (B-cells) in the marginal zone of secondary lymphoid follicles within the spl

When people mention today’s medicine, precision plays one of the most crucial roles and human lives are literally dependent on it. Likewise, any researches related to medicine are required to meet the highest standards. The challenge nowadays is that any conclusions of researches can be shared online and used as a reference without being adequately checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this challenge and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to validate publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with corresponding scores higher than 100 as wel

When public speak of contemporary medicine, precision plays one of the most crucial roles and human lives are directly dependent on it. Likewise, any researches pertaining to medicine are required to meet the highest standards. The issue today is that any conclusions of researches can be shared online and used as a reference without being precisely checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with respective scores above 100 as w

For women with mutations in the right gene, the risk of hereditary breast cancer can increase to over 80%. The BRCA gene, so named because of its role in suppressing BReast CAncer,, normally acts to repair damage to DNA and prevent the harmful mutations that can lead to rampant growth. In patients with some mutations of the BRCA gene, however, the chances of breast and ovarian cancer go up substantially. Women at risk for hereditary breast cancer have several preventative treatment options, but they tend to be quite radical. Preventative surgery to remove the breasts, ovaries, and fallopian tubes are effective in preventing cancer, but also quite invasive. In a new study published in Oncotarget, researchers in the Netherlands sought out a less-invasive preventative treatment for women at risk for breast cancer due to a BRCA mutation. hospitals in usa New-York hospital Los Angeles hospital Finding New Preventative Measures for Breast Cancer Drawing on previous research, the au

When public discuss today’s medicine, accuracy plays one of the most crucial roles and people’s lives are literally dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the top standards. The challenge nowadays is that any outcomes of researches can be posted online and used as a reference without being precisely checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality indicator. That helps both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with respective scores higher than 100 as

Researchers based out of Tokyo, Japan, recently experimented with testing new target mechanisms combined with antibody-drug conjugate (ADC) therapy to treat small cell lung cancer (SCLC). SCLC has maintained a relatively unimproved prognosis over the years and accounts for 10–15% of patients diagnosed with lung cancer. Antibodies are proteins that can be used to target foreign agents, such as viruses or bacteria, and other mechanisms in the body in need of regulation. ADC therapies work by adjoining antibodies with toxic agents. The ADCs are created to first, precisely pinpoint cancerous tumors using specially designed antibodies and then, to release cytotoxins delivering the tumor cells with a pharmaceutical drug that is thousands of times more potent than chemotherapy (without damaging the healthy cells nearby). Houston hospital Phoenix hospital Philadelphia hospital “We searched for transmembrane proteins of SCLC using a computational-biological approach. […] We identified tr

When people speak of modern medicine, accuracy plays one of the most crucial roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to comply with the highest standards. The challenge today is that any outcomes of researches can be published online and used as a reference without being precisely verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this challenge and tried to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with respective scores above 100 as well as

When people mention today’s medicine, accuracy plays one of the most important roles and people’s lives are directly dependent on it. Hence, any researches pertaining to medicine are required to comply with the top standards. The issue today is that any results of researches can be posted online and used as a reference without being thoroughly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores higher than 100 as well as rep

Canadian researchers found that quantitative ultrasound radiomics in late stage breast cancer patients accurately predicts tumor response to chemotherapy using texture derivatives in images via machine learning analysis. Ultrasound examination. Diagnosis and research of diseases with the help of ultrasound Ultrasound examination. Diagnosis and research of diseases with the help of ultrasound A team of multidisciplinary researchers from the University of Toronto, Sunnybrook Health Sciences Centre and Research Institute, and York University—all based out of Toronto, Canada—carried out a study that leads toward personalized oncology for later stage breast cancer patients. The study found that computer-generated analysis of ultrasound images can detect tumor response to upcoming chemotherapy with high accuracy through texture derivative analysis using machine learning algorithms. The Study Imaging is an important step in current oncological practice. Various imaging instruments, such a

When general population speak of modern medicine, accuracy plays one of the most important roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are required to comply with the top standards. The problem today is that any recommendations of researches can be shared online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective sc

In a case presentation paper, Encyclopedic Tumor Analysis guided researchers in identifying HER2 overexpression in a patient with distal common bile duct carcinoma and in personalizing his treatment regimen. Microscopic ductal cell carcinoma. Adenonocarcinoma from human breast cancer tissue. Magnification 400X Microscopic ductal cell carcinoma. Adenonocarcinoma from human breast cancer tissue. Magnification 400X The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — Researchers from multiple highly-regarded institutions located in India and from the Medical College of Wisconsin in the United states wrote a paper on the case presentation: “Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma w

When public refer to modern medicine, accuracy plays one of the most crucial roles and human lives are directly dependent on it. Likewise, any researches related to medicine are necessary to meet the top standards. The issue nowadays is that any conclusions of researches can be published online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a full publications list with respective scores above 100 as well as reports discussed previous